Publications:
- Metabolic Health:
- Effects of 12-week supplementation of Citrus bergamia extracts-based formulation CitriCholess on cholesterol and body weight in older adults with dyslipidemia: a randomized, double-blind, placebo controlled trial, Lipids in Health and Disease, 2017, :251, DOI: 10.1186/s12944-017-0640-1
- Postprandial glucose is more closely associated with the risk factors of diabetes than fasting glucose and glycosylated hemoglobin (HbA1c) in old adult with prediabetes: Beneficial Effects of Polyherbal Supplements—A Randomized, Double-Blind, Placebo Controlled Trial, Evidence-Based Complementary and Alternative Medicine, Volume 2019 (2019), Article ID 7923732., doi: 10.1155/2019/7923732
- Heterogeneously elevated branched-chain/aromatic amino acids among new-onset type-2 diabetes mellitus patients are potentially skewed diabetes predictors. World Journal of Diabetes, 15 January 2024, 15(1):53-71. doi: 10.4239/wjd.v15.i1.53
- Comparison of inflammatory, nutrient, and neurohormonal indicators in patients with schizophrenia, bipolar disorder, and major depressive disorder. Journal of Psychiatric Research , 2021 May;137:401-408. DOI: 10.1016/j.jpsychires.2021.03.010
- Adaptation and maladaptation to ambient hypoxia; Andean, Ethiopian and Himalayan patterns. PLoS One, 3(6):e2342, DOI: 10.1371/journal.pone.0002342
- Pancreatic insulin responses to exogenous glucose in Friesian heifers of low or high genetic merit for milk-fat yield. Animal Production, 56:171-178, DOI: https://doi.org/10.1017/S000335610002122X
- Diurnal variation in plasma metabolite and hormone concentrations and response to metabolic challenges in high breeding index and low breeding index Friesian heifers fed at two allowances. New Zealand Journal of Agricultural Research. 34 (3):295-304, https://doi.org/10.1080/00288233.1991.10417668
- Plasma metabolite and hormone concentrations in Friesian calves differing in genetic potential for milk-fat production. New Zealand Journal of Agricultural Research. 31:159-67, https://doi.org/10.1080/00288233.1988.10417941
- Gastrointestinal Tract Health:
- Blood pressure health:
- Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol. Lipids in Health and Disease, 2017,16(1) :253, DOI: 10.1186/s12944-017-0617-0
- Effects of 12-week Supplementation of a Polyherbal Formulation in Old Adults with Prehypertension/Hypertension in Older Adults with Prehypertension/hypertension: A Randomized, Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine, Volume 2019 (2019), Article ID 7056872, DOI: 10.1155/2019/7056872
- Cognitive Health:
- Evidence-based anti-inflammatory, anti-hypoperfusion and anti-anxiety/insomnia therapies show promises for TBI-induced post-traumatic symptoms and cognitive deficits. Frontiers in Neurology, 09 June 2021, Front. Neurol. DOI: 10.3389/fneur.2021.695629
- The Safety and Efficacy of BrainPower Advanced, a Dietary Supplement, in Older Adults with Subjective Memory Complaints: A Randomized, Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine, Volume 2016 (2016), Article ID 7898093, DOI: 10.1155/2016/7898093
- Playing mahjong for 12-weeks improved the executive function of the elderly with mild cognitive impairment: implication for TBI-induced cognitive deficits. Frontiers in Neurology, 27 March 2020, Front. Neurol. DOI: 10.3389/fneur.2020.00178
- Subjective Cognitive Decline and Related Cognitive Deficits. Front Neurol. 2020 May 19:11:247. DOI: 10.3389/fneur.2020.00247
- Advances in Resting State Neuroimaging of Mild Cognitive Impairment, Front Psychiatry. 2018 Dec 6:9:671. DOI: 10.3389/fpsyt.2018.00671
- Transcranial Direct Current Stimulation Improves Cognitive Function in Mild to Moderate Alzheimer Disease:A Meta-Analysis. Alzheimer Dis Assoc Disord. 2019 Apr-Jun;33(2):170-178., DOI: 10.1097/WAD.0000000000000304
- Effects of High-Frequency Transcranial Magnetic Stimulation for Cognitive Deficit in Schizophrenia: A Meta-Analysis. Frontiers in Psychiatry, 2019, doi: 10.3389/fpsyt.2019.00135
- - Comparison of screening effects of MoCA-B and MMSE in patients with Mild Cognitive Impairment. Medical Journal of West China, 2021, 33(8):1221-1229, DOI: 10. 3969/j.issn.1672-3511
- Repetitive transcranial magnetic stimulation as an alternative therapy for cognitive impairment in Alzheimer’s disease: Meta-Analysis. J Alzheimer’s Disease, 2015, 48: 463-472, DOI: 10.3233/JAD-150346
- Head/Brain Care:
- Effects of Yunanan Baiyao and Xingnaojing adjunct therapies on postoperative recovery and clinical prognosis of patients with traumatic brain injury: a randomized controlled trial. Phytomedicine, 2021 Aug:89:153593, DOI: 10.1016/j.phymed.2021.153593
- Effects of pyruvate administration on mitochondrial enzymes, neurological behaviors and neurodegeneration after traumatic brain injury. Aging & Disease, 2021, 12(4):983-999, DOI: 10.14336/AD.2020.1015
- Efficacy and safety of Panax Notoginseng saponin therapy for acute intracerebral hemorrhage: meta-analysis and potential mechanisms of action. Front. Neurol., 7 January 2015, DOI: 10.3389/fneur.2014.00274
- Folk moxibustion as an effective therapy for cerebral palsy: clinical evidence and in search of scientific explanation. Brain Stimulation, 2015, 8(2):421 (https://www.brainstimjrnl.com/article/S1935-861X(15)00767-6/abstract
- In vitro cytoprotection of resveratrol against H2O2-induced oxidative stress and apoptosis in astrocytes Journal of Behavior Therapy and mental health. Journal of Behavior Therapy and Mental Health 2016, 1(1):49-57, DOI 10.14302/issn.2474-9273.jbtm-16-1151)
- Metabolic Acetate Therapy for the Treatment of Traumatic Brain Injury. Journal of Neurotrauma, 27(1): 293-298, DOI: 10.1089/neu.2009.0994
- Divergent induction of branched-chain aminotransferases and phosphorylation of branched chain keto-acid dehydrogenase is a potential mechanism coupling BCKA -mediated-astrocyte activation to cognitive deficit after TBI, J Neurotrauma. 2018 Oct 15;35(20):2482-2494, DOI: 10.1089/neu.2017.5496/
- Controlled cortical impact injury and craniotomy result in divergent alterations of pyruvate metabolizing enzymes in rat brain. Experimental Neurology, 234; 31-38, DOI: 10.1016/j.expneurol.2011.12.007
- Pyruvate dehydrogenase phosphatase1 mRNA expression is divergently and dynamically regulated between rat cerebral cortex, hippocampus, and thalamus after traumatic brain injury: A potential biomarker of TBI-induced hyper- and hypo-glycaemia and neuronal vulnerability. Neuroscience Letters 525 (2012) 140– 145, DOI: 10.1016/j.neulet.2012.07.055
- Differential expression of brain cannabinoid receptors between repeatedly stressed males and females may play a role in age and gender-related difference in traumatic brain injury: Implications from animal studies. Frontiers in Neurology/Neurotrauma, 2014, 5: 161. DOI: 10.3389/fneur.2014.00161
- Impact of repeated stress on traumatic brain injury-induced mitochondrial electron transport chain expression and behavioral responses in rats. Frontiers in Neurology/Neurotrauma, 2013; 4: 196. doi: 10.3389/fneur.2013.00196
- Traumatic brain injury induced expression and phosphorylation of pyruvate dehydrogenase (PDH): a mechanism of dysregulated glucose metabolism. Neuroscience Letters, 454:38-42, DOI: 10.1016/j.neulet.2009.01.047
- Skin Health:
- Mental Health:
- Decreased calcium-dependent constitutive nitric oxide synthase (cNOS) activity in the prefrontal cortex of patients with schizophrenia and depression. Schizophrenia Res. 2002, 58:21-30, DOI: 10.1016/s0920-9964(01)00388-7
- Decreased Prefrontal CaMKII alpha mRNA in bipolar patients. NeuroReport. 2002, 13(4):501-505. DOI: 10.1097/00001756-200203250-00029
- Stress Impairs 5-HT(2A) Receptor-Mediated Serotonergic Facilitation of GABA Release in Juvenile Rat Basolateral Amygdala. Neuropsychoopharmacology, 2009, 34(2), 410-423, DOI: 10.1038/npp.2008.71
- Impact of repeated stress on traumatic brain injury-induced mitochondrial electron transport chain expression and behavioral responses in rats. Frontiers in Neurology/Neurotrauma, 2013; 4: 196. doi: 10.3389/fneur.2013.00196)
- Expression pattern of the cannabinoid receptor genes in the frontal cortex of mood disorder patients and mice selectively bred for high and low fear. Journal of Psychiatric Research. 2012, 46:882-889, DOI: 10.1016/j.jpsychires.2012.03.021
- Delayed effects of repeated inescapable severe stress on brain cannabinoid receptor expression and acoustic startle response in adolescent male rats: Relevance to the development of posttraumatic stress disorder and stress-related brain atrophy, in “Posttraumatic Stress Disorder: New Research”, Editors: Edward Foreman and Jay Fuller,2013, New York, Nova Publishers
- Cardiovascular health
- Gender- and lesion number-dependent difference in “atherogenic index of plasma” in Chinese people with coronary heart disease (Scientific Report, 2017 Oct 16;7(1):13207. DOI: 10.1038/s41598-017-13267-6)
- Association of CYP2C19 Polymorphism with Clopidogrel Resistance in Patients with Acute Coronary Syndrome in China. Med Sci Monit. 2019; 25:7138-7148 , DOI: 10.12659/MSM.915971
- Left main coronary artery fistula to superior vena cava: a case report. BJR Case Rep., 2016; (v2)2: 20150387. doi: 10.1259/bjrcr.20150387
- Functional health
- Short- and Long-term Effects of Repetitive Transcranial Magnetic Stimulation on Upper Limb Motor Function after Stroke: A Systematic Review and Meta-Analysis. Clin Rehabil. 2017 Sep;31(9):1137-1153. DOI: 10.1177/0269215517692386
- Low Frequency Repetitive Transcranial Magnetic Stimulation for Stroke-induced Upper Limb Motor Deficit: A Meta-Analysis. Neural Plasticity, 2017; 2017: 2758097, DOI: 10.1155/2017/2758097
- Maternal deprivation increases cell death in the infant rat brain. Developmental Brain Research; 133(1): 1-11. DOI: 10.1016/s0926-6410(01)00118-5
- Rat Nurr1 is prominently expressed in perirhinal cortex, and differentially induced by electroconvulsive vs. kindled seizures. Mol. Brain Res. 47:251-261, DOI: 10.1016/s0169-328x (97)00056-9
- Q Ipsilesional High Frequency Repetitive Transcranial Magnetic Stimulation Add-on Therapy Improved Diffusion Parameters of Stroke Patients with Motor Dysfunction: A Preliminary DTI Study. Neural Plasticity, 2016:6238575. DOI: 10.1155/2016/6238575
- Repetitive Transcranial Magnetic Stimulation as an Alternative Therapy for Dysphagia after Stroke: A Meta-Analysis. Clinical Rehabilitation, 2017, 31(3):289-298. DOI: 10.1177/0269215516644771
- Modulation of Interhemispheric Activation Balance in Motor-Related Areas of Stroke Patients with Motor Recovery: Systematic Review and Meta-analysis of fMRI Studies. Neuroscience & Biological Reviews, 2015, 47:392-400, DOI: 10.1016/j.neubiorev.2015.09.003
- High Frequency Repetitive Transcranial Magnetic Stimulation Therapy for Chronic Neuropathic Pain: A Meta-Analysis. Pain Physician, 2015; 18(6): E1029-E1046, DOI:10.36076/ppj.2015/18/E1029
- Kainate receptor-mediated heterosynaptic facilitation in the amygdala. Nature Neuroscience 4:612-620, DOI: 10.1038/88432
- A Systematic Review for the Therapeutic Effects of Sleep Deprivation on Depression with Repetitive Transcranial Magnetic Stimulation. BMC Psychiatry, 2015, 15:282, DOI: 10.1186/s12888-015-0674-8
- Biomarkers:
- A biomarker study showed that heterogeneously elevated branched-chain/aromatic amino acids are potentially skewed diabetes predictors of type-2 diabetes mellitus. World Journal of Diabetes, 15 January 2024, 15(1):53-71. doi: 10.4239/wjd.v15.i1.53
- Childhood gene expression predicts subsequent chronic mountain sickness. BMC Pediatrics, 2008, 8 (47): 1-9, doi: 10.1186/1471-2431-8-47
- Cannabinoid receptor expression and phosphorylation are differentially regulated between male and female cerebellum and brainstem after repeated stress: implication for PTSD and drug abuse. Neuroscience Letters 512:5-9. DOI: 10.1016/j.neulet.2011.05.013
- Biomarkers in an animal model for revealing neural, hematologic, and behavioral correlates of PTSD Journal of Visualized Experiments. 2012 Oct 10;(68): 3361 pii: 3361. DOI: 10.3791/3361
- Overexpression of serotonin receptor and transporter mRNA in blood leukocytes of antipsychotic-free and antipsychotic-naïve schizophrenic patients: Gender differences. Schizophrenia Res. 121:160-171, DOI: 10.1016/j.schres.2010.03.030
- Expression pattern of the cannabinoid receptor genes in the frontal cortex of mood disorder patients and mice selectively bred for high and low fear. Journal of Psychiatric Research 46:882-889, DOI: 10.1016/j.jpsychires.2012.03.021
- PTSD risk is associated with BDNF Val66Met and BDNF overexpression. Molecular Psychiatry, (2014) 19, 8–10; DOI: 10.1038/mp.2012.180