Lotus Biotech has relentlessly committed to excellence and passion for transforming scientific discoveries into health promoting supplements/products for the ageing population. Below is a list of our completed supplement projects in collaboration with supplement companies, medical institutions, hospitals, community healthcare centers:

• 1) A randomized, double-blind, placebo-controlled trial tested the effects of 12-week supplementation of Citrus bergamia extracts-based formulation on cholesterol and body weight in older adults with dyslipidemia (Lipids in Health and Disease, 2017, :251)
• 2) A 12-week Randomized, Double-Blind, Placebo-Controlled Trial that evaluated the Safety and Efficacy of a Dietary Supplement in Older Adults with Subjective Memory Complaints (Evidence-Based Complementary and Alternative Medicine, Volume 2016 (2016), Article ID 7898093)
• 3) A Randomized, Double-Blind, Placebo-Controlled Trial that evaluated the Safety and Efficacy of 12-week Supplementation of Marine Omega-3 PUFA-based Formulation in Older Adults with Prehypertension and/or Hypercholesterolemia (Lipids in Health and Disease, 2017,16(1) :253)
• 4) A 12-week randomized, double-blind, placebo-controlled trial tested the effects of a polyherbal supplementation on fasting glucose, postprandial glucose and glycosylated hemoglobin (HbA1c) in old adult with prediabetes (Evidence-Based Complementary and Alternative Medicine, Volume 2019 (2019), Article ID 7923732., doi:
• 5) A Randomized, Double-Blind, Placebo-Controlled Trial evaluated the effects of 12-week Supplementation of a Polyherbal Formulation in Old Adults with Prehypertension/Hypertension (Evidence-Based Complementary and Alternative Medicine, Volume 2019 (2019), Article ID 7056872, doi: 10.1155/2019/7056872.)
• 6) A 12-week randomized, double-blind, placebo-controlled trial tested the relieving effects of a polyherbal-based dietary supplement on gastrointestinal quality of life index (GIQLI) in older adults with chronic gastrointestinal symptoms (Evidence-Based Complementary and Alternative Medicine, vol. 2021, Article ID 6653550, 13 pages, 2021. https://doi.org/10.1155/2021/6653550)
• 7) An observational study compared the different status in inflammation, nutrition, and neurohormonal levels between patients with schizophrenia, bipolar disorder and major depressive disorder, Journal of Psychiatric Research , 2021 May;137:401-408. DOI: 10.1016/j.jpsychires.2021.03.010)
• 8) An animal model study examined the relieving effects of a herbal decoction on Cuprizone-Induced Demyelination and Behavioral Deficits in mice（Neural Plasticity, 2021 Feb 25;2021:8812362. DOI: 10.1155/2021/8812362）
• 9) A randomized controlled trial examined the therapeutic effects of two phytotherapies (Yunanan Baiyao, Xingnaojing) on postoperative recovery and clinical prognosis of patients with traumatic brain injury (Phytomedicine, 2021 May 14;89:153593. doi: 10.1016/j.phymed.2021.153593)
• 10) A biomarker study showed that heterogeneously elevated branched-chain/aromatic amino acids are potentially skewed diabetes predictors of type-2 diabetes mellitus (World Journal of Diabetes, 15 January 2024, 15(1):53-71. doi: 10.4239/wjd.v15.i1.53)
• 11) A system review and meta-analysis of the efficacy, safety and mechanisms of action of Panax Notoginseng saponin therapy for acute intracerebral hemorrhage (Front. Neurol., 7 January 2015, DOI: 10.3389/fneur.2014.00274).
• 12) Evidence-based anti-inflammatory, anti-hypoperfusion and anti-anxiety/insomnia therapies as promising therapies for post-traumatic symptoms and cognitive deficits (Frontiers in Neurology, 09 June 2021, Front. Neurol. doi: 10.3389/fneur.2021.695629)
• 13) A case report of the therapeutic effects of a pure topical herbal medicine on diabetic foot ulcer (World Journal of Complex Medicine, 2015, 2:85-87, doi 10.11966/j.issn.2095- 994X.2015.01.02.00).
• 14) Reported clinical evidence that moxibustion acupuncture is an effective therapy for cerebral palsy (Brain Stimulation, 2015, 8(2):421)
• 15) Completed a 12-week randomized control trial (phase II study) that examined the safety and efficacy of a tea phytonutrient in old adults with type 2 diabetes (to be published)
• 16) Completed a community survey that examined the interactions between ageing, cognition, and metabolic/nutritional status in old adults with subjective cognitive decline (to be published)
• 17) US patent pending (Application#: 17/812.171, 07/12/2022)